Aortic Aneurysm Generation in Mice with Targeted Deletion of Integrin Linked Kinase (ILK) in Vascular Smooth Muscle Cells

RATIONALE: Integrin-linked kinase (ILK) is located at focal adhesions and links the extracellular matrix (ECM) to the actin cytoskeleton via β1- and β3-integrins. ILK plays a role in the activation of kinases including protein kinase B/Akt and glycogen synthase kinase 3β (GSK3β), and regulates cell...

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Main Authors: Shen, Dongxiao, Li, Jian, Lepore, John J., Anderson, Thomas J.T., Sinha, Sumita, Lin, Alexander Y., Cheng, Lan, Cohen, Ethan David, Roberts, Jesse D., Dedhar, Shoukat, Parmacek, Michael S., Gerszten, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351207/
https://ncbi.nlm.nih.gov/pubmed/21778429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.239343
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