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Aortic Aneurysm Generation in Mice with Targeted Deletion of Integrin Linked Kinase (ILK) in Vascular Smooth Muscle Cells
RATIONALE: Integrin-linked kinase (ILK) is located at focal adhesions and links the extracellular matrix (ECM) to the actin cytoskeleton via β1- and β3-integrins. ILK plays a role in the activation of kinases including protein kinase B/Akt and glycogen synthase kinase 3β (GSK3β), and regulates cell...
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| Autors principals: | , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3351207/ https://ncbi.nlm.nih.gov/pubmed/21778429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.239343 |
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