DSAGE Identifies Osteopontin as a Downstream Effector of Integrin-Linked Kinase (ILK) in Cardiac-Specific ILK Knockout Mice

BACKGROUND: Integrin-linked kinase (ILK) is a serine-threonine kinase that has been linked to human and experimental heart failure, but its role in the heart is not fully understood. METHODS AND RESULTS: To define the role of cardiomyocyte ILK, we generated cardiac-specific ILK knockout mice (CSILK-...

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Main Authors: Dai, Jing, Matsui, Takashi, Abel, E. Dale, Dedhar, Shoukat, Gerszten, Robert E., Seidman, Christine E., Seidman, J. G., Rosenzweig, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950354/
https://ncbi.nlm.nih.gov/pubmed/24319095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.113.000649
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