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Osteoclast-specific inactivation of the Integrin-Linked Kinase (ILK) inhibits bone resorption
Bone resorption requires the adhesion of osteoclasts to extracellular matrix (ECM) components, a process mediated by the α(v)β(3) integrin. Following engagement with the ECM, integrin receptors signal via multiple downstream effectors, including the Integrin-Linked Kinase (ILK). In order to characte...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3995416/ https://ncbi.nlm.nih.gov/pubmed/20564195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22609 |
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