Osteoclast-specific inactivation of the Integrin-Linked Kinase (ILK) inhibits bone resorption

Bone resorption requires the adhesion of osteoclasts to extracellular matrix (ECM) components, a process mediated by the α(v)β(3) integrin. Following engagement with the ECM, integrin receptors signal via multiple downstream effectors, including the Integrin-Linked Kinase (ILK). In order to characte...

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Detalhes bibliográficos
Main Authors: Dossa, Tanya, Arabian, Alice, Windle, Jolene J., Dedhar, Shoukat, Teitelbaum, Steven L., Ross, F. Patrick, Roodman, G. David, St-Arnaud, René
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995416/
https://ncbi.nlm.nih.gov/pubmed/20564195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22609
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