Impaired Hair Follicle Morphogenesis and Polarized Keratinocyte Movement upon Conditional Inactivation of Integrin-linked Kinase in the Epidermis

Integrin-linked kinase (ILK) is key for cell survival, migration, and adhesion, but little is known about its role in epidermal development and homeostasis in vivo. We generated mice with conditional inactivation of the Ilk gene in squamous epithelia. These mice die perinatally and exhibit skin blis...

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Autors principals: Nakrieko, Kerry-Ann, Welch, Ian, Dupuis, Holly, Bryce, Dawn, Pajak, Agnieszka, St. Arnaud, René, Dedhar, Shoukat, D'Souza, Sudhir J. A., Dagnino, Lina
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2008
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291395/
https://ncbi.nlm.nih.gov/pubmed/18234842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-06-0526
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