Integrin-linked kinase is required for epidermal and hair follicle morphogenesis

Integrin-linked kinase (ILK) links integrins to the actin cytoskeleton and is believed to phosphorylate several target proteins. We report that a keratinocyte-restricted deletion of the ILK gene leads to epidermal defects and hair loss. ILK-deficient epidermal keratinocytes exhibited a pronounced in...

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Autori principali: Lorenz, Katrin, Grashoff, Carsten, Torka, Robert, Sakai, Takao, Langbein, Lutz, Bloch, Wilhelm, Aumailley, Monique, Fässler, Reinhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2007
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064816/
https://ncbi.nlm.nih.gov/pubmed/17485490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200608125
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