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Integrin-linked kinase is required for epidermal and hair follicle morphogenesis
Integrin-linked kinase (ILK) links integrins to the actin cytoskeleton and is believed to phosphorylate several target proteins. We report that a keratinocyte-restricted deletion of the ILK gene leads to epidermal defects and hair loss. ILK-deficient epidermal keratinocytes exhibited a pronounced in...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The Rockefeller University Press
2007
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2064816/ https://ncbi.nlm.nih.gov/pubmed/17485490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200608125 |
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