Integrin-Linked Kinase Deletion from Mouse Cortex Results in Cortical Lamination Defects Resembling Cobblestone Lissencephaly

Integrin-linked kinase (Ilk) is a scaffold and kinase that links integrin receptors to the actin cytoskeleton and to signaling pathways involved in cell adhesion, migration, and extracellular matrix deposition. Targeted deletion of Ilk from embryonic mouse dorsal forebrain neuroepithelium results in...

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Detalhes bibliográficos
Main Authors: Niewmierzycka, Agnieszka, Mills, Julia, St-Arnaud, Rene, Dedhar, Shoukat, Reichardt, Louis F.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Development/Plasticity/Repair
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688706/
https://ncbi.nlm.nih.gov/pubmed/16049178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1695-05.2005
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