Targeted Deletion of Integrin-Linked Kinase Reveals a Role in T-Cell Chemotaxis and Survival

Integrin-linked kinase (ILK) is a serine/threonine kinase that is important in cell-matrix interactions and cell signaling. To examine the role of ILK in leukocyte trafficking and survival, we generated T cell-specific ILK knockouts by breeding ILK(flox/flox) mice to transgenic mice expressing Cre r...

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Detaylı Bibliyografya
Asıl Yazarlar: Liu, Emerson, Sinha, Sumita, Williams, Christine, Cyrille, Marcoli, Heller, Eric, Snapper, Scott B., Georgopoulos, Katia, St-Arnaud, Rene, Force, Thomas, Dedhar, Shoukat, Gerszten, Robert E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2005
Konular:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1316981/
https://ncbi.nlm.nih.gov/pubmed/16314534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.24.11145-11155.2005
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