Mechanism of the formation of DNA–protein cross-links by antitumor cisplatin

Por Chválová, Kateřina, Brabec, Viktor, Kašpárková, Jana
Publicado em 2007

DNA bending and unwinding due to the major 1,2-GG intrastrand cross-link formed by antitumor cis-diamminedichloroplatinum(II) are flanking-base independent

Por Stehlikova, Kristyna, Kostrhunova, Hana, Kasparkova, Jana, Brabec, Viktor
Publicado em 2002

Differential recognition by the tumor suppressor protein p53 of DNA modified by the novel antitumor trinuclear platinum drug BBR3464 and cisplatin

Por Kasparkova, Jana, Fojta, Miroslav, Farrell, Nicholas, Brabec, Viktor
Publicado em 2004

Effects of Monofunctional Adducts of Platinum(II) Complexes on Thermodynamic Stability and Energetics of DNA Duplexes

Por Bursova, Vendula, Kasparkova, Jana, Hofr, Ctirad, Brabec, Viktor
Publicado em 2005

Biophysical Studies on the Stability of DNA Intrastrand Cross-Links of Transplatin

Por Kasparkova, Jana, Marini, Victoria, Bursova, Vendula, Brabec, Viktor
Publicado em 2008

Walking of antitumor bifunctional trinuclear Pt(II) complex on double-helical DNA

Por Malina, Jaroslav, Kasparkova, Jana, Farrell, Nicholas P., Brabec, Viktor
Publicado em 2011

Inhibition of nuclear factor kappaB proteins-platinated DNA interactions correlates with cytotoxic effectiveness of the platinum complexes

Por Brabec, Viktor, Kasparkova, Jana, Kostrhunova, Hana, Farrell, Nicholas P.
Publicado no Sci Rep (2016)

DNA–protein cross-linking by trans-[PtCl(2)(E-iminoether)(2)]. A concept for activation of the trans geometry in platinum antitumor complexes

Por Novakova, Olga, Kasparkova, Jana, Malina, Jaroslav, Natile, Giovanni, Brabec, Viktor
Publicado em 2003

Chiral discrimination in platinum anticancer drugs.

Por Benedetti, Michele, Malina, Jaroslav, Kasparkova, Jana, Brabec, Viktor, Natile, Giovanni
Publicado em 2002

Conformation, protein recognition and repair of DNA interstrand and intrastrand cross-links of Antitumor trans-[PtCl(2)(NH(3))(thiazole)]

Por Marini, Victoria, Christofis, Petros, Novakova, Olga, Kasparkova, Jana, Farrell, Nicholas, Brabec, Viktor
Publicado em 2005

Conformation and recognition of DNA modified by a new antitumor dinuclear Pt(II) complex resistant to decomposition by sulfur nucleophiles

Por Zerzankova, Lenka, Suchankova, Tereza, Vrana, Oldrich, Farrell, Nicholas P., Brabec, Viktor, Kasparkova, Jana
Publicado em 2009

Double-check probing of DNA bending and unwinding by XPA–RPA: an architectural function in DNA repair

Por Missura, Miriam, Buterin, Tonko, Hindges, Robert, Hübscher, Ulrich, Kaspárková, Jana, Brabec, Viktor, Naegeli, Hanspeter
Publicado em 2001

Amide-Based Prodrugs of Spermidine-Bridged Dinuclear Platinum. Synthesis, DNA Binding, and Biological Activity

Por Hegmans, Alexander, Kasparkova, Jana, Vrana, Oldrich, Kelland, Lloyd R., Brabec, Viktor, Farrell, Nicholas P.
Publicado em 2008

Potentiating Effect of UVA Irradiation on Anticancer Activity of Carboplatin Derivatives Involving 7-Azaindoles

Por Štarha, Pavel, Trávníček, Zdeněk, Dvořák, Zdeněk, Radošová-Muchová, Tereza, Prachařová, Jitka, Vančo, Ján, Kašpárková, Jana
Publicado no PLoS One (2015)

Epigenetic and antitumor effects of platinum(IV)-octanoato conjugates

Por Novohradsky, Vojtech, Zanellato, Ilaria, Marzano, Cristina, Pracharova, Jitka, Kasparkova, Jana, Gibson, Dan, Gandin, Valentina, Osella, Domenico, Brabec, Viktor
Publicado no Sci Rep (2017)

Factors Affecting DNA–DNA Interstrand Cross-Links in the Antiparallel 3′–3′ Sense: A Comparison with the 5′–5′ Directional Isomer

Por Ruhayel, Rasha A., Moniodis, Joseph J., Yang, Xiaohong, Kasparkova, Jana, Brabec, Viktor, Berners-Price, Susan J., Farrell, Nicholas P.
Publicado em 2009

A potent cytotoxic photoactivated platinum complex

Por Mackay, Fiona S., Woods, Julie A., Heringová, Pavla, Kašpárková, Jana, Pizarro, Ana M., Moggach, Stephen A., Parsons, Simon, Brabec, Viktor, Sadler, Peter J.
Publicado em 2007

Replacement of a Thiourea with an Amidine Group in a Monofunctional Platinum–acridine Antitumor Agent. Effect on DNA Interactions, DNA Adduct Recognition and Repair

Por Kostrhunova, Hana, Malina, Jaroslav, Pickard, Amanda J., Stepankova, Jana, Vojtiskova, Marie, Kašpárkova, Jana, Muchova, Tereza, Rohlfing, Matthew L., Bierbach, Ulrich, Brabec, Viktor
Publicado em 2011

Diazido Mixed-Amine Platinum(IV) Anticancer Complexes Activatable by Visible-Light Form Novel DNA Adducts

Por Zhao, Yao, Woods, Julie A, Farrer, Nicola J, Robinson, Kim S, Pracharova, Jitka, Kasparkova, Jana, Novakova, Olga, Li, Huilin, Salassa, Luca, Pizarro, Ana M, Clarkson, Guy J, Song, Lijiang, Brabec, Viktor, Sadler, Peter J
Publicado no Chemistry (2013)