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Effects of Monofunctional Adducts of Platinum(II) Complexes on Thermodynamic Stability and Energetics of DNA Duplexes

Effects of adducts of [PtCl(NH(3))(3)]Cl or chlorodiethylenetriamineplatinum(II) on DNA stability were studied with emphasis on thermodynamic origins of that stability. Oligodeoxyribonucleotide duplexes (15-bp) containing the single, site-specific monofunctional adduct at G-residues of the central s...

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Detalhes bibliográficos
Main Authors: Bursova, Vendula, Kasparkova, Jana, Hofr, Ctirad, Brabec, Viktor
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305123/
https://ncbi.nlm.nih.gov/pubmed/15574710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.051771
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