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Monofunctional DNA-platinum(II) adducts block frequently DNA polymerases.

The question of whether monofunctional DNA platinum(II) adducts block synthesis of DNA by purified DNA polymerases of different types and origin has been investigated by comparing the time dependence of synthesis arrest and of DNA adduct formation. Activated salmon testis DNA is used as a suitable s...

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Bibliografische gegevens
Hoofdauteurs: Holler, E, Bauer, R, Bernges, F
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1992
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC312346/
https://ncbi.nlm.nih.gov/pubmed/1594449
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