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Monofunctional DNA-platinum(II) adducts block frequently DNA polymerases.

The question of whether monofunctional DNA platinum(II) adducts block synthesis of DNA by purified DNA polymerases of different types and origin has been investigated by comparing the time dependence of synthesis arrest and of DNA adduct formation. Activated salmon testis DNA is used as a suitable s...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Holler, E, Bauer, R, Bernges, F
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1992
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312346/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1594449/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.9.2307
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