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Monofunctional DNA-platinum(II) adducts block frequently DNA polymerases.

The question of whether monofunctional DNA platinum(II) adducts block synthesis of DNA by purified DNA polymerases of different types and origin has been investigated by comparing the time dependence of synthesis arrest and of DNA adduct formation. Activated salmon testis DNA is used as a suitable s...

詳細記述

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書誌詳細
主要な著者: Holler, E, Bauer, R, Bernges, F
フォーマット: Artigo
言語:Inglês
出版事項: 1992
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC312346/
https://ncbi.nlm.nih.gov/pubmed/1594449
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