Factors Affecting DNA–DNA Interstrand Cross-Links in the Antiparallel 3′–3′ Sense: A Comparison with the 5′–5′ Directional Isomer

Reported herein is a study of the unusual 3′–3′ 1,4-GG interstrand cross-link (IXL) formation in duplex DNA by a series of polynuclear platinum anticancer complexes. To examine the effect of possible preassociation through charge and hydrogen-bonding effects the closely related compounds [{trans-PtC...

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Hlavní autoři: Ruhayel, Rasha A., Moniodis, Joseph J., Yang, Xiaohong, Kasparkova, Jana, Brabec, Viktor, Berners-Price, Susan J., Farrell, Nicholas P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810863/
https://ncbi.nlm.nih.gov/pubmed/19691069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.200900958
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