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Factors Affecting DNA–DNA Interstrand Cross-Links in the Antiparallel 3′–3′ Sense: A Comparison with the 5′–5′ Directional Isomer
Reported herein is a study of the unusual 3′–3′ 1,4-GG interstrand cross-link (IXL) formation in duplex DNA by a series of polynuclear platinum anticancer complexes. To examine the effect of possible preassociation through charge and hydrogen-bonding effects the closely related compounds [{trans-PtC...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2810863/ https://ncbi.nlm.nih.gov/pubmed/19691069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.200900958 |
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