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Walking of antitumor bifunctional trinuclear Pt(II) complex on double-helical DNA

The trinuclear BBR3464 ([{trans-PtCl(NH(3))(2)}(2)µ-(trans-Pt(NH(3))(2)(H(2)N(CH(2))(6)NH(2))(2))](4+)) belongs to the polynuclear class of platinum-based anticancer agents. DNA adducts of this complex differ significantly in structure and type from those of clinically used mononuclear platinum comp...

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Bibliografiske detaljer
Main Authors: Malina, Jaroslav, Kasparkova, Jana, Farrell, Nicholas P., Brabec, Viktor
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025560/
https://ncbi.nlm.nih.gov/pubmed/20833634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq803
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