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Walking of antitumor bifunctional trinuclear Pt(II) complex on double-helical DNA
The trinuclear BBR3464 ([{trans-PtCl(NH(3))(2)}(2)µ-(trans-Pt(NH(3))(2)(H(2)N(CH(2))(6)NH(2))(2))](4+)) belongs to the polynuclear class of platinum-based anticancer agents. DNA adducts of this complex differ significantly in structure and type from those of clinically used mononuclear platinum comp...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025560/ https://ncbi.nlm.nih.gov/pubmed/20833634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq803 |
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