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Substitution-inert trinuclear platinum complexes efficiently condense/aggregate nucleic acids and inhibit enzymatic activity
The trinuclear platinum complexes ([{Pt(NH(3))(3)}(2)-μ-{trans-Pt(NH(3))(2)(NH(2)(CH(2))(6)NH(2))(2)}](6+), TriplatinNC‐A; [{trans-Pt(NH(3))(2)(NH(2)(CH(2))(6)NH(3)(+))}(2)-μ-{trans-Pt(NH(3))(2)(NH(2)(CH(2))(6)NH(2))(2)}](8+), TriplatinNC) belong to a class of biologically active agents that bind to...
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| Publicado en: | Angew Chem Int Ed Engl |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4311996/ https://ncbi.nlm.nih.gov/pubmed/25256921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201408012 |
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