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Mechanism of the formation of DNA–protein cross-links by antitumor cisplatin

DNA–protein cross-links are formed by various DNA-damaging agents including antitumor platinum drugs. The natures of these ternary DNA–Pt–protein complexes (DPCLs) can be inferred, yet much remains to be learned about their structures and mechanisms of formation. We investigated the origin of these...

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Detalhes bibliográficos
Main Authors: Chválová, Kateřina, Brabec, Viktor, Kašpárková, Jana
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874601/
https://ncbi.nlm.nih.gov/pubmed/17329374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm032
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