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Mechanism of the formation of DNA–protein cross-links by antitumor cisplatin

DNA–protein cross-links are formed by various DNA-damaging agents including antitumor platinum drugs. The natures of these ternary DNA–Pt–protein complexes (DPCLs) can be inferred, yet much remains to be learned about their structures and mechanisms of formation. We investigated the origin of these...

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Détails bibliographiques
Auteurs principaux: Chválová, Kateřina, Brabec, Viktor, Kašpárková, Jana
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874601/
https://ncbi.nlm.nih.gov/pubmed/17329374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm032
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