A Stochastic Step Model of Replicative Senescence Explains ROS Production Rate in Ageing Cell Populations

Por Lawless, Conor, Jurk, Diana, Gillespie, Colin S., Shanley, Daryl, Saretzki, Gabriele, von Zglinicki, Thomas, Passos, João F.
Publicado em 2012

A senescent cell bystander effect: senescence-induced senescence

Por Nelson, Glyn, Wordsworth, James, Wang, Chunfang, Jurk, Diana, Lawless, Conor, Martin-Ruiz, Carmen, von Zglinicki, Thomas
Publicado em 2012

Adult-onset, short-term dietary restriction reduces cell senescence in mice

Por Wang, Chunfang, Maddick, Mandy, Miwa, Satomi, Jurk, Diana, Czapiewski, Rafal, Saretzki, Gabriele, Langie, Sabine A.S., Godschalk, Roger W.L., Cameron, Kerry, von Zglinicki, Thomas
Publicado em 2010

Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence

Por Hewitt, Graeme, Jurk, Diana, Marques, Francisco D.M., Correia-Melo, Clara, Hardy, Timothy, Gackowska, Agata, Anderson, Rhys, Taschuk, Morgan, Mann, Jelena, Passos, João F.
Publicado em 2012

Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response

Por Jurk, Diana, Wang, Chunfang, Miwa, Satomi, Maddick, Mandy, Korolchuk, Viktor, Tsolou, Avgi, Gonos, Efstathios S, Thrasivoulou, Christopher, Jill Saffrey, M, Cameron, Kerry, von Zglinicki, Thomas
Publicado em 2012

Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice

Por Roos, Carolyn M., Zhang, Bin, Palmer, Allyson K., Ogrodnik, Mikolaj B., Pirtskhalava, Tamar, Thalji, Nassir M., Hagler, Michael, Jurk, Diana, Smith, Leslie A., Casaclang‐Verzosa, Grace, Zhu, Yi, Schafer, Marissa J., Tchkonia, Tamara, Kirkland, James L., Miller, Jordan D.
Publicado no Aging Cell (2016)

DNA damage response at telomeres contributes to lung aging and chronic obstructive pulmonary disease

Por Birch, Jodie, Anderson, Rhys K., Correia-Melo, Clara, Jurk, Diana, Hewitt, Graeme, Marques, Francisco Madeira, Green, Nicola J., Moisey, Elizabeth, Birrell, Mark A., Belvisi, Maria G., Black, Fiona, Taylor, John J., Fisher, Andrew J., De Soyza, Anthony, Passos, João F.
Publicado no Am J Physiol Lung Cell Mol Physiol (2015)

SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair

Por Hewitt, Graeme, Carroll, Bernadette, Sarallah, Rezazadeh, Correia-Melo, Clara, Ogrodnik, Mikołaj, Nelson, Glyn, Otten, Elsje G., Manni, Diego, Antrobus, Robin, Morgan, Brian A., von Zglinicki, Thomas, Jurk, Diana, Seluanov, Andrei, Gorbunova, Vera, Johansen, Terje, Passos, João F., Korolchuk, Viktor I.
Publicado no Autophagy (2016)

Chronic inflammation induces telomere dysfunction and accelerates ageing in mice

Por Jurk, Diana, Wilson, Caroline, Passos, João F., Oakley, Fiona, Correia-Melo, Clara, Greaves, Laura, Saretzki, Gabriele, Fox, Chris, Lawless, Conor, Anderson, Rhys, Hewitt, Graeme, Pender, Sylvia LF, Fullard, Nicola, Nelson, Glyn, Mann, Jelena, van de Sluis, Bart, Mann, Derek A., von Zglinicki, Thomas
Publicado em 2014

Oxidative stress and life histories: unresolved issues and current needs

Por Speakman, John R., Blount, Jonathan D., Bronikowski, Anne M., Buffenstein, Rochelle, Isaksson, Caroline, Kirkwood, Tom B. L., Monaghan, Pat, Ozanne, Susan E., Beaulieu, Michaël, Briga, Michael, Carr, Sarah K., Christensen, Louise L., Cochemé, Helena M., Cram, Dominic L., Dantzer, Ben, Harper, Jim M., Jurk, Diana, King, Annette, Noguera, Jose C., Salin, Karine, Sild, Elin, Simons, Mirre J. P., Smith, Shona, Stier, Antoine, Tobler, Michael, Vitikainen, Emma, Peaker, Malcolm, Selman, Colin
Publicado no Ecol Evol (2015)

Mitochondria are required for pro‐ageing features of the senescent phenotype

Por Correia‐Melo, Clara, Marques, Francisco DM, Anderson, Rhys, Hewitt, Graeme, Hewitt, Rachael, Cole, John, Carroll, Bernadette M, Miwa, Satomi, Birch, Jodie, Merz, Alina, Rushton, Michael D, Charles, Michelle, Jurk, Diana, Tait, Stephen WG, Czapiewski, Rafal, Greaves, Laura, Nelson, Glyn, Bohlooly‐Y, Mohammad, Rodriguez‐Cuenca, Sergio, Vidal‐Puig, Antonio, Mann, Derek, Saretzki, Gabriele, Quarato, Giovanni, Green, Douglas R, Adams, Peter D, von Zglinicki, Thomas, Korolchuk, Viktor I, Passos, João F
Publicado no EMBO J (2016)

17α-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization

Por Stout, Michael B., Steyn, Frederik J., Jurczak, Michael J., Camporez, Joao-Paulo G., Zhu, Yi, Hawse, John R., Jurk, Diana, Palmer, Allyson K., Xu, Ming, Pirtskhalava, Tamar, Evans, Glenda L., de Souza Santos, Roberta, Frank, Aaron P., White, Thomas A., Monroe, David G., Singh, Ravinder J., Casaclang-Verzosa, Grace, Miller, Jordan D., Clegg, Deborah J., LeBrasseur, Nathan K., von Zglinicki, Thomas, Shulman, Gerald I., Tchkonia, Tamara, Kirkland, James L.
Publicado no J Gerontol A Biol Sci Med Sci (2017)