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DNA damage response at telomeres contributes to lung aging and chronic obstructive pulmonary disease

Cellular senescence has been associated with the structural and functional decline observed during physiological lung aging and in chronic obstructive pulmonary disease (COPD). Airway epithelial cells are the first line of defense in the lungs and are important to COPD pathogenesis. However, the mec...

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Bibliografski detalji
Izdano u:Am J Physiol Lung Cell Mol Physiol
Glavni autori: Birch, Jodie, Anderson, Rhys K., Correia-Melo, Clara, Jurk, Diana, Hewitt, Graeme, Marques, Francisco Madeira, Green, Nicola J., Moisey, Elizabeth, Birrell, Mark A., Belvisi, Maria G., Black, Fiona, Taylor, John J., Fisher, Andrew J., De Soyza, Anthony, Passos, João F.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652155/
https://ncbi.nlm.nih.gov/pubmed/26386121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00293.2015
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