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Chronic inflammation induces telomere dysfunction and accelerates ageing in mice
Chronic inflammation is associated with normal and pathological ageing. Here we show that chronic, progressive low-grade inflammation induced by knockout of the nfkb1 subunit of the transcription factor NF-κB induces premature ageing in mice. We also show that these mice have reduced regeneration in...
Tallennettuna:
| Päätekijät: | , , , , , , , , , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Pub. Group
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4090717/ https://ncbi.nlm.nih.gov/pubmed/24960204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5172 |
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