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Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence
Telomeres are specialized nucleoprotein structures, which protect chromosome ends and have been implicated in the ageing process. Telomere shortening has been shown to contribute to a persistent DNA damage response (DDR) during replicative senescence, the irreversible loss of division potential of s...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Pub. Group
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3292717/ https://ncbi.nlm.nih.gov/pubmed/22426229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1708 |
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