Non-Canonical Wnt Predominates in Activated Rat Hepatic Stellate Cells, Influencing HSC Survival and Paracrine Stimulation of Kupffer Cells

Por Corbett, Laura, Mann, Jelena, Mann, Derek A.
Publicado no PLoS One (2015)

The mechanisms of HSC activation and epigenetic regulation of HSCs phenotypes

Por Page, Agata, Mann, Derek A., Mann, Jelena
Publicado no Curr Pathobiol Rep (2014)

Epigenetic cell fate regulation of hepatic stellate cells

Por Tsukamoto, Hidekazu, Zhu, Nian-Ling, Asahina, Kinji, Mann, Derek A., Mann, Jelena
Publicado no Hepatol Res (2011)

Hepatic Stellate Cell Transdifferentiation Involves Genome-Wide Remodeling of the DNA Methylation Landscape

Por Page, Agata, Paoli, Pier, Salvador, Eva Moran, White, Steve, French, Jeremy, Mann, Jelena
Publicado no J Hepatol (2015)

The NF-κB p50:p50:HDAC-1 repressor complex orchestrates transcriptional inhibition of multiple pro-inflammatory genes

Por Elsharkawy, Ahmed M., Oakley, Fiona, Lin, Feng, Packham, Graham, Mann, Derek A., Mann, Jelena
Publicado em 2010

An experimental study to identify the potential role of pharmacogenomics in determining the occurrence of oxaliplatin-induced liver injury

Por Robinson, Stuart M, Mann, Jelena, Manas, Derek M, Mann, Derek A, White, Steven A
Publicado em 2013

MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis

Por Mann, Jelena, Chu, David CK, Maxwell, Aidan, Oakley, Fiona, Zhu, Nian-Ling, Tsukamoto, Hidekazu, Mann, Derek A
Publicado em 2009

Cross-talk between DNA methylation and active histone modifications regulates aberrant expression of ZAP70 in CLL

Por Amin, Shilu, Walsh, Meagan, Wilson, Caroline, Parker, Anton E, Oscier, David, Willmore, Elaine, Mann, Derek, Mann, Jelena
Publicado em 2012

Rosmarinic acid and baicalin epigenetically de-repress Pparγ in hepatic stellate cells for their anti-fibrotic effect

Por Yang, Melissa D., Chiang, Yi-Ming, Higashiyama, Reiichi, Asahina, Kinji, Mann, Derek A., Mann, Jelena, Wang, Clay, Tsukamoto, Hidekazu
Publicado em 2012

Allele-Specific Regulation of Matrix Metalloproteinase-3 Gene by Transcription Factor NFκB

Por Souslova, Veronika, Townsend, Paul A., Mann, Jelena, van der Loos, Chris M., Motterle, Anna, D'Acquisto, Fulvio, Mann, Derek A., Ye, Shu
Publicado em 2010

Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence

Por Hewitt, Graeme, Jurk, Diana, Marques, Francisco D.M., Correia-Melo, Clara, Hardy, Timothy, Gackowska, Agata, Anderson, Rhys, Taschuk, Morgan, Mann, Jelena, Passos, João F.
Publicado em 2012

Glucose Induces Protein Targeting to Glycogen in Hepatocytes by Fructose 2,6-Bisphosphate-Mediated Recruitment of MondoA to the Promoter

Por Petrie, John L., Al-Oanzi, Ziad H., Arden, Catherine, Tudhope, Susan J., Mann, Jelena, Kieswich, Julius, Yaqoob, Muhammad M., Towle, Howard C., Agius, Loranne
Publicado em 2013

Differential DNA methylation of genes involved in fibrosis progression in non-alcoholic fatty liver disease and alcoholic liver disease

Por Zeybel, Müjdat, Hardy, Timothy, Robinson, Stuart M, Fox, Christopher, Anstee, Quentin M, Ness, Thomas, Masson, Steven, Mathers, John C, French, Jeremy, White, Steve, Mann, Jelena
Publicado no Clin Epigenetics (2015)

Alcohol Directly Stimulates Epigenetic Modifications in Hepatic Stellate Cells

Por Page, Agata, Paoli, Pier P., Hill, Stephen J., Howarth, Rachel, Wu, Raymond, Kweon, Soo-Mi, French, Jeremy, White, Steve, Tsukamoto, Hidekazu, Mann, Derek A., Mann, Jelena
Publicado no J Hepatol (2014)

Nuclear Factor-κB1 (p50) Limits the Inflammatory and Fibrogenic Responses to Chronic Injury

Por Oakley, Fiona, Mann, Jelena, Nailard, Sarah, Smart, David E., Mungalsingh, Narendra, Constandinou, Christothea, Ali, Shakir, Wilson, Susan J., Millward-Sadler, Harry, Iredale, John P., Mann, Derek A.
Publicado em 2005

DNA methylation profiling identifies novel markers of progression in hepatitis B-related chronic liver disease

Por Zeybel, Müjdat, Vatansever, Sezgin, Hardy, Timothy, Sarı, Ayşegül Akder, Cakalağaoğlu, Fulya, Avcı, Arzu, Zeybel, Gemma Louise, Karahüseyinoğlu, Serçin, Bashton, Matthew, Mathers, John C., Ünsal, Belkıs, Mann, Jelena
Publicado no Clin Epigenetics (2016)

Low-strength T-cell activation promotes Th17 responses

Por Purvis, Harriet A., Stoop, Jeroen N., Mann, Jelena, Woods, Steven, Kozijn, Anne E., Hambleton, Sophie, Robinson, John H., Isaacs, John D., Anderson, Amy E., Hilkens, Catharien M. U.
Publicado em 2010

Histone Methyltransferase ASH1 Orchestrates Fibrogenic Gene Transcription During Myofibroblast Transdifferentiation

Por Perugorria, Maria Jesus, Wilson, Caroline L, Zeybel, Mujdat, Walsh, Meagan, Amin, Shilu, Robinson, Stuart, White, Steven A, Burt, Alastair D, Oakley, Fiona, Tsukamoto, Hidekazu, Mann, Derek A, Mann, Jelena
Publicado em 2012

Quiescent Hepatic Stellate Cells Functionally Contribute to the Hepatic Innate Immune Response via TLR3

Por Wilson, Caroline L., Mann, Jelena, Walsh, Meagan, Perrugoria, Maria J., Oakley, Fiona, Wright, Matthew C., Brignole, Chiara, Di Paolo, Daniela, Perri, Patrizia, Ponzoni, Mirco, Karin, Michael, Mann, Derek A.
Publicado em 2014

Plasma DNA methylation: a potential biomarker for stratification of liver fibrosis in non-alcoholic fatty liver disease

Por Hardy, Timothy, Zeybel, Mujdat, Day, Christopher P, Dipper, Christian, Masson, Steven, McPherson, Stuart, Henderson, Elsbeth, Tiniakos, Dina, White, Steve, French, Jeremy, Mann, Derek A, Anstee, Quentin M, Mann, Jelena
Publicado no Gut (2017)