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Rosmarinic acid and baicalin epigenetically de-repress Pparγ in hepatic stellate cells for their anti-fibrotic effect

Hepatic stellate cells (HSCs) undergo myofibroblastic trans-differentiation (activation) to participate in liver fibrosis, and identification of molecular targets for this cell fate regulation is essential for development of efficacious therapeutic modalities for the disease. Peroxisomal proliferato...

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Hlavní autoři: Yang, Melissa D., Chiang, Yi-Ming, Higashiyama, Reiichi, Asahina, Kinji, Mann, Derek A., Mann, Jelena, Wang, Clay, Tsukamoto, Hidekazu
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302956/
https://ncbi.nlm.nih.gov/pubmed/22095555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24792
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