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Hepatic Stellate Cell Transdifferentiation Involves Genome-Wide Remodeling of the DNA Methylation Landscape

BACKGROUND AND AIMS: DNA methylation is an epigenetic mark that is an established regulator of transcriptional repression with an important role in liver fibrosis. Currently, there is very little knowledge available as to how DNA methylation controls the phenotype of hepatic stellate cell (HSC), the...

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Bibliografske podrobnosti
izdano v:J Hepatol
Main Authors: Page, Agata, Paoli, Pier, Salvador, Eva Moran, White, Steve, French, Jeremy, Mann, Jelena
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904781/
https://ncbi.nlm.nih.gov/pubmed/26632634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2015.11.024
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