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Hepatic Stellate Cell Transdifferentiation Involves Genome-Wide Remodeling of the DNA Methylation Landscape

BACKGROUND AND AIMS: DNA methylation is an epigenetic mark that is an established regulator of transcriptional repression with an important role in liver fibrosis. Currently, there is very little knowledge available as to how DNA methylation controls the phenotype of hepatic stellate cell (HSC), the...

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Detalhes bibliográficos
Publicado no:J Hepatol
Main Authors: Page, Agata, Paoli, Pier, Salvador, Eva Moran, White, Steve, French, Jeremy, Mann, Jelena
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904781/
https://ncbi.nlm.nih.gov/pubmed/26632634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2015.11.024
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