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Hepatic Stellate Cell Transdifferentiation Involves Genome-Wide Remodeling of the DNA Methylation Landscape

BACKGROUND AND AIMS: DNA methylation is an epigenetic mark that is an established regulator of transcriptional repression with an important role in liver fibrosis. Currently, there is very little knowledge available as to how DNA methylation controls the phenotype of hepatic stellate cell (HSC), the...

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Bibliographische Detailangaben
Veröffentlicht in:J Hepatol
Hauptverfasser: Page, Agata, Paoli, Pier, Salvador, Eva Moran, White, Steve, French, Jeremy, Mann, Jelena
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904781/
https://ncbi.nlm.nih.gov/pubmed/26632634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2015.11.024
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