MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis

BACKGROUND & AIMS: Myofibroblast transdifferentiation generates hepatic myofibroblasts, which promote liver fibrogenesis. The peroxisome proliferator-activated receptor (PPAR)γ is a negative regulator of this process. We investigated epigenetic regulation of PPARγ and myofibroblast transdifferen...

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Autori principali: Mann, Jelena, Chu, David CK, Maxwell, Aidan, Oakley, Fiona, Zhu, Nian-Ling, Tsukamoto, Hidekazu, Mann, Derek A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819585/
https://ncbi.nlm.nih.gov/pubmed/19843474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.10.002
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