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Zebularine suppresses TGF-beta-induced lens epithelial cell–myofibroblast transdifferentiation by inhibiting MeCP2

PURPOSE: Posterior capsular opacification (PCO) is a common long-term complication of modern cataract surgery. Remnant lens epithelial cells (LECs) undergo a myofibroblast transdifferentiation that is thought to be the initial step of PCO pathogenesis. The purpose of this study is to determine the e...

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Main Authors: Zhou, Peng, Lu, Yi, Sun, Xing-Huai
Formato: Artigo
Idioma:Inglês
Publicado: Molecular Vision 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209433/
https://ncbi.nlm.nih.gov/pubmed/22065925
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