Histone Methyltransferase ASH1 Orchestrates Fibrogenic Gene Transcription During Myofibroblast Transdifferentiation

Transdifferentiation of hepatic stellate cells (HSCs) to a myofibroblast-like phenotype is the pivotal event in liver fibrosis. The dramatic change in phenotype associated with transdifferentiation is underpinned by a global change in gene expression. Orchestrated changes in gene expression take pla...

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Detalhes bibliográficos
Main Authors: Perugorria, Maria Jesus, Wilson, Caroline L, Zeybel, Mujdat, Walsh, Meagan, Amin, Shilu, Robinson, Stuart, White, Steven A, Burt, Alastair D, Oakley, Fiona, Tsukamoto, Hidekazu, Mann, Derek A, Mann, Jelena
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2012
Assuntos:
Liver Biology/Pathobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430805/
https://ncbi.nlm.nih.gov/pubmed/22488473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25754
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