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Telomere dysfunction promotes transdifferentiation of human fibroblasts into myofibroblasts

Cells that had undergone telomere dysfunction‐induced senescence secrete numerous cytokines and other molecules, collectively called the senescence‐associated secretory phenotype (SASP). Although certain SASP factors have been demonstrated to promote cellular senescence in neighboring cells in a par...

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Bibliografske podrobnosti
izdano v:Aging Cell
Main Authors: Razdan, Neetu, Vasilopoulos, Themistoklis, Herbig, Utz
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260909/
https://ncbi.nlm.nih.gov/pubmed/30244523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12838
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