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Telomere dysfunction promotes transdifferentiation of human fibroblasts into myofibroblasts

Cells that had undergone telomere dysfunction‐induced senescence secrete numerous cytokines and other molecules, collectively called the senescence‐associated secretory phenotype (SASP). Although certain SASP factors have been demonstrated to promote cellular senescence in neighboring cells in a par...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Razdan, Neetu, Vasilopoulos, Themistoklis, Herbig, Utz
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260909/
https://ncbi.nlm.nih.gov/pubmed/30244523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12838
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