DNA damage response at telomeres contributes to lung aging and chronic obstructive pulmonary disease

Cellular senescence has been associated with the structural and functional decline observed during physiological lung aging and in chronic obstructive pulmonary disease (COPD). Airway epithelial cells are the first line of defense in the lungs and are important to COPD pathogenesis. However, the mec...

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I publikationen:Am J Physiol Lung Cell Mol Physiol
Huvudupphovsmän: Birch, Jodie, Anderson, Rhys K., Correia-Melo, Clara, Jurk, Diana, Hewitt, Graeme, Marques, Francisco Madeira, Green, Nicola J., Moisey, Elizabeth, Birrell, Mark A., Belvisi, Maria G., Black, Fiona, Taylor, John J., Fisher, Andrew J., De Soyza, Anthony, Passos, João F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2015
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Call for Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652155/
https://ncbi.nlm.nih.gov/pubmed/26386121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00293.2015
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