DNA damage response at telomeres contributes to lung aging and chronic obstructive pulmonary disease

Cellular senescence has been associated with the structural and functional decline observed during physiological lung aging and in chronic obstructive pulmonary disease (COPD). Airway epithelial cells are the first line of defense in the lungs and are important to COPD pathogenesis. However, the mec...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Birch, Jodie, Anderson, Rhys K., Correia-Melo, Clara, Jurk, Diana, Hewitt, Graeme, Marques, Francisco Madeira, Green, Nicola J., Moisey, Elizabeth, Birrell, Mark A., Belvisi, Maria G., Black, Fiona, Taylor, John J., Fisher, Andrew J., De Soyza, Anthony, Passos, João F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Call for Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652155/
https://ncbi.nlm.nih.gov/pubmed/26386121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00293.2015
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