Demystifying the role of mitochondria in senescence

door Correia-Melo, Clara, Passos, João F.
Gepubliceerd in Mol Cell Oncol (2016)

Telomeres, oxidative stress and inflammatory factors: partners in cellular senescence?

door Correia-Melo, Clara, Hewitt, Graeme, Passos, João F
Gepubliceerd in 2014

Powering senescence: The ugly side of mitochondria

door Correia-Melo, Clara, Birch, Jodie, Passos, João F.
Gepubliceerd in Cell Cycle (2016)

Pyphe, a python toolbox for assessing microbial growth and cell viability in high-throughput colony screens

door Kamrad, Stephan, Rodríguez-López, María, Cotobal, Cristina, Correia-Melo, Clara, Ralser, Markus, Bähler, Jürg
Gepubliceerd in eLife (2020)

CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity

door Manning, Amity L, Bakhoum, Samuel F, Maffini, Stefano, Correia-Melo, Clara, Maiato, Helder, Compton, Duane A
Gepubliceerd in 2010

Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence

door Hewitt, Graeme, Jurk, Diana, Marques, Francisco D.M., Correia-Melo, Clara, Hardy, Timothy, Gackowska, Agata, Anderson, Rhys, Taschuk, Morgan, Mann, Jelena, Passos, João F.
Gepubliceerd in 2012

Pyruvate kinase variant of fission yeast tunes carbon metabolism, cell regulation, growth and stress resistance

door Kamrad, Stephan, Grossbach, Jan, Rodríguez‐López, Maria, Mülleder, Michael, Townsend, StJohn, Cappelletti, Valentina, Stojanovski, Gorjan, Correia‐Melo, Clara, Picotti, Paola, Beyer, Andreas, Ralser, Markus, Bähler, Jürg
Gepubliceerd in Mol Syst Biol (2020)

Rapamycin improves healthspan but not inflammaging in nfκb1 (−/−) mice

door Correia‐Melo, Clara, Birch, Jodie, Fielder, Edward, Rahmatika, Dina, Taylor, Jennifer, Chapman, James, Lagnado, Anthony, Carroll, Bernadette M., Miwa, Satomi, Richardson, Gavin, Jurk, Diana, Oakley, Fiona, Mann, Jelena, Mann, Derek A., Korolchuk, Viktor I., Passos, João F.
Gepubliceerd in Aging Cell (2018)

Lysine harvesting is an antioxidant strategy and triggers underground polyamine metabolism

door Olin-Sandoval, Viridiana, Yu, Jason Shu Lim, Miller-Fleming, Leonor, Alam, Mohammad Tauqeer, Kamrad, Stephan, Correia-Melo, Clara, Haas, Robert, Segal, Joanna, Navarro, David Alejandro Peña, Herrera-Dominguez, Lucia, Méndez-Lucio, Oscar, Vowinckel, Jakob, Mülleder, Michael, Ralser, Markus
Gepubliceerd in Nature (2019)

DNA damage response at telomeres contributes to lung aging and chronic obstructive pulmonary disease

door Birch, Jodie, Anderson, Rhys K., Correia-Melo, Clara, Jurk, Diana, Hewitt, Graeme, Marques, Francisco Madeira, Green, Nicola J., Moisey, Elizabeth, Birrell, Mark A., Belvisi, Maria G., Black, Fiona, Taylor, John J., Fisher, Andrew J., De Soyza, Anthony, Passos, João F.
Gepubliceerd in Am J Physiol Lung Cell Mol Physiol (2015)

SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair

door Hewitt, Graeme, Carroll, Bernadette, Sarallah, Rezazadeh, Correia-Melo, Clara, Ogrodnik, Mikołaj, Nelson, Glyn, Otten, Elsje G., Manni, Diego, Antrobus, Robin, Morgan, Brian A., von Zglinicki, Thomas, Jurk, Diana, Seluanov, Andrei, Gorbunova, Vera, Johansen, Terje, Passos, João F., Korolchuk, Viktor I.
Gepubliceerd in Autophagy (2016)

Chronic inflammation induces telomere dysfunction and accelerates ageing in mice

door Jurk, Diana, Wilson, Caroline, Passos, João F., Oakley, Fiona, Correia-Melo, Clara, Greaves, Laura, Saretzki, Gabriele, Fox, Chris, Lawless, Conor, Anderson, Rhys, Hewitt, Graeme, Pender, Sylvia LF, Fullard, Nicola, Nelson, Glyn, Mann, Jelena, van de Sluis, Bart, Mann, Derek A., von Zglinicki, Thomas
Gepubliceerd in 2014

Mitochondria are required for pro‐ageing features of the senescent phenotype

door Correia‐Melo, Clara, Marques, Francisco DM, Anderson, Rhys, Hewitt, Graeme, Hewitt, Rachael, Cole, John, Carroll, Bernadette M, Miwa, Satomi, Birch, Jodie, Merz, Alina, Rushton, Michael D, Charles, Michelle, Jurk, Diana, Tait, Stephen WG, Czapiewski, Rafal, Greaves, Laura, Nelson, Glyn, Bohlooly‐Y, Mohammad, Rodriguez‐Cuenca, Sergio, Vidal‐Puig, Antonio, Mann, Derek, Saretzki, Gabriele, Quarato, Giovanni, Green, Douglas R, Adams, Peter D, von Zglinicki, Thomas, Korolchuk, Viktor I, Passos, João F
Gepubliceerd in EMBO J (2016)

Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence

door Anderson, Rhys, Lagnado, Anthony, Maggiorani, Damien, Walaszczyk, Anna, Dookun, Emily, Chapman, James, Birch, Jodie, Salmonowicz, Hanna, Ogrodnik, Mikolaj, Jurk, Diana, Proctor, Carole, Correia‐Melo, Clara, Victorelli, Stella, Fielder, Edward, Berlinguer‐Palmini, Rolando, Owens, Andrew, Greaves, Laura C, Kolsky, Kathy L, Parini, Angelo, Douin‐Echinard, Victorine, LeBrasseur, Nathan K, Arthur, Helen M, Tual‐Chalot, Simon, Schafer, Marissa J, Roos, Carolyn M, Miller, Jordan D, Robertson, Neil, Mann, Jelena, Adams, Peter D, Tchkonia, Tamara, Kirkland, James L, Mialet‐Perez, Jeanne, Richardson, Gavin D, Passos, João F
Gepubliceerd in EMBO J (2019)