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CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity

Accurate chromosome segregation during mitosis requires precise coordination of various processes, such as chromosome alignment, maturation of proper kinetochore–microtubule (kMT) attachments, correction of erroneous attachments, and silencing of the spindle assembly checkpoint (SAC). How these fund...

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Bibliografiske detaljer
Main Authors: Manning, Amity L, Bakhoum, Samuel F, Maffini, Stefano, Correia-Melo, Clara, Maiato, Helder, Compton, Duane A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964175/
https://ncbi.nlm.nih.gov/pubmed/20852589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.230
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