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CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity

Accurate chromosome segregation during mitosis requires precise coordination of various processes, such as chromosome alignment, maturation of proper kinetochore–microtubule (kMT) attachments, correction of erroneous attachments, and silencing of the spindle assembly checkpoint (SAC). How these fund...

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Detalhes bibliográficos
Main Authors: Manning, Amity L, Bakhoum, Samuel F, Maffini, Stefano, Correia-Melo, Clara, Maiato, Helder, Compton, Duane A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964175/
https://ncbi.nlm.nih.gov/pubmed/20852589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.230
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