Cdk1 and Plk1 mediate a CLASP2 phospho-switch that stabilizes kinetochore–microtubule attachments

Accurate chromosome segregation during mitosis relies on a dynamic kinetochore (KT)–microtubule (MT) interface that switches from a labile to a stable condition in response to correct MT attachments. This transition is essential to satisfy the spindle-assembly checkpoint (SAC) and couple MT-generate...

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Autores principales: Maia, Ana R.R., Garcia, Zaira, Kabeche, Lilian, Barisic, Marin, Maffini, Stefano, Macedo-Ribeiro, Sandra, Cheeseman, Iain M., Compton, Duane A., Kaverina, Irina, Maiato, Helder
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2012
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471233/
https://ncbi.nlm.nih.gov/pubmed/23045552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201203091
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