Modelling the Response of FOXO Transcription Factors to Multiple Post-Translational Modifications Made by Ageing-Related Signalling Pathways

Por Smith, Graham R., Shanley, Daryl P.
Publicado em 2010

Computational modelling of the regulation of Insulin signalling by oxidative stress

Por Smith, Graham R, Shanley, Daryl P
Publicado em 2013

Evolution, stress, and longevity

Por KIRKWOOD, THOMAS B. L., KAPAHI, PANKAJ, SHANLEY, DARYL P.
Publicado em 2000

Systems Modelling of NHEJ Reveals the Importance of Redox Regulation of Ku70/80 in the Dynamics of DNA Damage Foci

Por Dolan, David, Nelson, Glyn, Zupanic, Anze, Smith, Graham, Shanley, Daryl
Publicado em 2013

Testing evolutionary theories of menopause

Por Shanley, Daryl P, Sear, Rebecca, Mace, Ruth, Kirkwood, Thomas B.L
Publicado em 2007

Modeling and gene knockdown to assess the contribution of nonsense-mediated decay, premature termination, and selenocysteine insertion to the selenoprotein hierarchy

Por Zupanic, Anze, Meplan, Catherine, Huguenin, Grazielle V.B., Hesketh, John E., Shanley, Daryl P.
Publicado no RNA (2016)

A Stochastic Step Model of Replicative Senescence Explains ROS Production Rate in Ageing Cell Populations

Por Lawless, Conor, Jurk, Diana, Gillespie, Colin S., Shanley, Daryl, Saretzki, Gabriele, von Zglinicki, Thomas, Passos, João F.
Publicado em 2012

Integrated Stochastic Model of DNA Damage Repair by Non-homologous End Joining and p53/p21- Mediated Early Senescence Signalling

Por Dolan, David W. P., Zupanic, Anze, Nelson, Glyn, Hall, Philip, Miwa, Satomi, Kirkwood, Thomas B. L., Shanley, Daryl P.
Publicado no PLoS Comput Biol (2015)

Detecting translational regulation by change point analysis of ribosome profiling data sets

Por Zupanic, Anze, Meplan, Catherine, Grellscheid, Sushma N., Mathers, John C., Kirkwood, Tom B.L., Hesketh, John E., Shanley, Daryl P.
Publicado em 2014

Dynamic Modelling of Pathways to Cellular Senescence Reveals Strategies for Targeted Interventions

Por Dalle Pezze, Piero, Nelson, Glyn, Otten, Elsje G., Korolchuk, Viktor I., Kirkwood, Thomas B. L., von Zglinicki, Thomas, Shanley, Daryl P.
Publicado em 2014

Genome‐Wide MicroRNA and Gene Analysis of Mesenchymal Stem Cell Chondrogenesis Identifies an Essential Role and Multiple Targets for miR‐140‐5p

Por Barter, Matt J., Tselepi, Maria, Gómez, Rodolfo, Woods, Steven, Hui, Wang, Smith, Graham R., Shanley, Daryl P., Clark, Ian M., Young, David A.
Publicado no Stem Cells (2015)

Increasing extracellular H(2)O(2) produces a bi-phasic response in intracellular H(2)O(2), with peroxiredoxin hyperoxidation only triggered once the cellular H(2)O(2)-buffering cap...

Por Tomalin, Lewis Elwood, Day, Alison Michelle, Underwood, Zoe Elizabeth, Smith, Graham Robert, Dalle Pezze, Piero, Rallis, Charalampos, Patel, Waseema, Dickinson, Bryan Craig, Bähler, Jürg, Brewer, Thomas Francis, Chang, Christopher Joh-Leung, Shanley, Daryl Pierson, Veal, Elizabeth Ann
Publicado no Free Radic Biol Med (2016)

A systems study reveals concurrent activation of AMPK and mTOR by amino acids

Por Pezze, Piero Dalle, Ruf, Stefanie, Sonntag, Annika G., Langelaar-Makkinje, Miriam, Hall, Philip, Heberle, Alexander M., Navas, Patricia Razquin, van Eunen, Karen, Tölle, Regine C., Schwarz, Jennifer J., Wiese, Heike, Warscheid, Bettina, Deitersen, Jana, Stork, Björn, Fäßler, Erik, Schäuble, Sascha, Hahn, Udo, Horvatovich, Peter, Shanley, Daryl P., Thedieck, Kathrin
Publicado no Nat Commun (2016)