Testing Biochemistry Revisited: How In Vivo Metabolism Can Be Understood from In Vitro Enzyme Kinetics

Por van Eunen, Karen, Kiewiet, José A. L., Westerhoff, Hans V., Bakker, Barbara M.
Publicado em 2012

The promiscuous enzyme medium-chain 3-keto-acyl-CoA thiolase triggers a vicious cycle in fatty-acid beta-oxidation

Por Martines, Anne-Claire M. F., van Eunen, Karen, Reijngoud, Dirk-Jan, Bakker, Barbara M.
Publicado no PLoS Comput Biol (2017)

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

Por den Besten, Gijs, van Eunen, Karen, Groen, Albert K., Venema, Koen, Reijngoud, Dirk-Jan, Bakker, Barbara M.
Publicado em 2013

Molecular mechanisms of mTOR regulation by stress

Por Heberle, Alexander Martin, Prentzell, Mirja Tamara, van Eunen, Karen, Bakker, Barbara Marleen, Grellscheid, Sushma Nagaraja, Thedieck, Kathrin
Publicado no Mol Cell Oncol (2014)

SYSTEMS BIOLOGY FROM MICROORGANISMS TO HUMAN METABOLIC DISEASES – THE ROLE OF DETAILED KINETIC MODELS

Por Bakker, Barbara M., van Eunen, Karen, Jeneson, Jeroen A.L., van Riel, Natal A.W., Bruggeman, Frank J., Teusink, Bas
Publicado em 2010

Oncogenic β-catenin and PIK3CA instruct network states and cancer phenotypes in intestinal organoids

Por Riemer, Pamela, Rydenfelt, Mattias, Marks, Matthias, van Eunen, Karen, Thedieck, Kathrin, Herrmann, Bernhard G., Blüthgen, Nils, Sers, Christine, Morkel, Markus
Publicado no J Cell Biol (2017)

The Short-Chain Fatty Acid Uptake Fluxes by Mice on a Guar Gum Supplemented Diet Associate with Amelioration of Major Biomarkers of the Metabolic Syndrome

Por den Besten, Gijs, Havinga, Rick, Bleeker, Aycha, Rao, Shodhan, Gerding, Albert, van Eunen, Karen, Groen, Albert K., Reijngoud, Dirk-Jan, Bakker, Barbara M.
Publicado em 2014

Protection against the Metabolic Syndrome by Guar Gum-Derived Short-Chain Fatty Acids Depends on Peroxisome Proliferator-Activated Receptor γ and Glucagon-Like Peptide-1

Por den Besten, Gijs, Gerding, Albert, van Dijk, Theo H., Ciapaite, Jolita, Bleeker, Aycha, van Eunen, Karen, Havinga, Rick, Groen, Albert K., Reijngoud, Dirk-Jan, Bakker, Barbara M.
Publicado no PLoS One (2015)

Biochemical Competition Makes Fatty-Acid β-Oxidation Vulnerable to Substrate Overload

Por van Eunen, Karen, Simons, Sereh M. J., Gerding, Albert, Bleeker, Aycha, den Besten, Gijs, Touw, Catharina M. L., Houten, Sander M., Groen, Bert K., Krab, Klaas, Reijngoud, Dirk-Jan, Bakker, Barbara M.
Publicado em 2013

Living on the edge: substrate competition explains loss of robustness in mitochondrial fatty-acid oxidation disorders

Por van Eunen, Karen, Volker-Touw, Catharina M. L., Gerding, Albert, Bleeker, Aycha, Wolters, Justina C., van Rijt, Willemijn J., Martines, Anne-Claire M. F., Niezen-Koning, Klary E., Heiner, Rebecca M., Permentier, Hjalmar, Groen, Albert K., Reijngoud, Dirk-Jan, Derks, Terry G. J., Bakker, Barbara M.
Publicado no BMC Biol (2016)

A systems study reveals concurrent activation of AMPK and mTOR by amino acids

Por Pezze, Piero Dalle, Ruf, Stefanie, Sonntag, Annika G., Langelaar-Makkinje, Miriam, Hall, Philip, Heberle, Alexander M., Navas, Patricia Razquin, van Eunen, Karen, Tölle, Regine C., Schwarz, Jennifer J., Wiese, Heike, Warscheid, Bettina, Deitersen, Jana, Stork, Björn, Fäßler, Erik, Schäuble, Sascha, Hahn, Udo, Horvatovich, Peter, Shanley, Daryl P., Thedieck, Kathrin
Publicado no Nat Commun (2016)