Wird geladen...
Oncogenic β-catenin and PIK3CA instruct network states and cancer phenotypes in intestinal organoids
Colorectal cancer is driven by cooperating oncogenic mutations. In this study, we use organotypic cultures derived from transgenic mice inducibly expressing oncogenic β-catenin and/or PIK3CA(H1047R) to follow sequential changes in cancer-related signaling networks, intestinal cell metabolism, and ph...
Gespeichert in:
| Veröffentlicht in: | J Cell Biol |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2017
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5461020/ https://ncbi.nlm.nih.gov/pubmed/28442534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201610058 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|