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SYSTEMS BIOLOGY FROM MICROORGANISMS TO HUMAN METABOLIC DISEASES – THE ROLE OF DETAILED KINETIC MODELS
Human metabolic diseases are typically network diseases. This holds not only for multifactorial diseases, such as metabolic syndrome or type II diabetes: even when a single gene defect is the primary cause, the adaptive response of the entire network determines the severity of disease. The latter ma...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3298031/ https://ncbi.nlm.nih.gov/pubmed/20863302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST0381294 |
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