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Gene network requirements for regulation of metabolic gene expression to a desired state

Gene circuits that control metabolism should restore metabolic functions upon environmental changes. Whether gene networks are capable of steering metabolism to optimal states is an open question. Here we present a method to identify such optimal gene networks. We show that metabolic network optimis...

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Détails bibliographiques
Auteurs principaux: Berkhout, Jan, Teusink, Bas, Bruggeman, Frank J.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593220/
https://ncbi.nlm.nih.gov/pubmed/23475326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01417
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