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Gene network requirements for regulation of metabolic gene expression to a desired state

Gene circuits that control metabolism should restore metabolic functions upon environmental changes. Whether gene networks are capable of steering metabolism to optimal states is an open question. Here we present a method to identify such optimal gene networks. We show that metabolic network optimis...

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Detalhes bibliográficos
Main Authors: Berkhout, Jan, Teusink, Bas, Bruggeman, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593220/
https://ncbi.nlm.nih.gov/pubmed/23475326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01417
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