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Molecular mechanisms of mTOR regulation by stress

Tumors are prime examples of cell growth in unfavorable environments that elicit cellular stress. The high metabolic demand and insufficient vascularization of tumors cause a deficiency of oxygen and nutrients. Oncogenic mutations map to signaling events via mammalian target of rapamycin (mTOR), met...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Heberle, Alexander Martin, Prentzell, Mirja Tamara, van Eunen, Karen, Bakker, Barbara Marleen, Grellscheid, Sushma Nagaraja, Thedieck, Kathrin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904989/
https://ncbi.nlm.nih.gov/pubmed/27308421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.970489
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