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Detecting translational regulation by change point analysis of ribosome profiling data sets

Ribo-Seq maps the location of translating ribosomes on mature mRNA transcripts. While during normal translation, ribosome density is constant along the length of the mRNA coding region, this can be altered in response to translational regulatory events. In the present study, we developed a method to...

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Detalles Bibliográficos
Main Authors: Zupanic, Anze, Meplan, Catherine, Grellscheid, Sushma N., Mathers, John C., Kirkwood, Tom B.L., Hesketh, John E., Shanley, Daryl P.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174433/
https://ncbi.nlm.nih.gov/pubmed/25147239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.045286.114
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