CD301b(+) mononuclear phagocytes maintain positive energy balance through secretion of resistin-like molecule (RELM) alpha

Por Kumamoto, Yosuke, Camporez, Joao Paulo G., Jurczak, Michael J., Shanabrough, Marya, Horvath, Tamas, Shulman, Gerald, Iwasaki, Akiko
Publicado no Immunity (2016)

Genetic activation of pyruvate dehydrogenase alters oxidative substrate selection to induce skeletal muscle insulin resistance

Por Rahimi, Yasmeen, Camporez, João-Paulo G., Petersen, Max C., Pesta, Dominik, Perry, Rachel J., Jurczak, Michael J., Cline, Gary W., Shulman, Gerald I.
Publicado no Proc Natl Acad Sci U S A (2014)

Reply to Constantin-Teodosiu et al.: Mice with genetic PDH activation are not protected from high-fat diet–induced muscle insulin resistance

Por Petersen, Max C., Rahimi, Yasmeen, Camporez, Joao-Paulo G., Pesta, Dominik, Perry, Rachel J., Jurczak, Michael J., Cline, Gary W., Shulman, Gerald I.
Publicado no Proc Natl Acad Sci U S A (2015)

Mechanism for the Anti-Diabetic Effect of Leptin

Por Perry, Rachel J., Zhang, Xian-Man, Zhang, Dongyan, Kumashiro, Naoki, Camporez, Joao-Paulo G., Cline, Gary W., Rothman, Douglas L., Shulman, Gerald I.
Publicado no Nat Med (2014)

ApoA5 knockdown improves whole-body insulin sensitivity in high-fat-fed mice by reducing ectopic lipid content

Por Camporez, João Paulo G., Kanda, Shoichi, Petersen, Max C., Jornayvaz, François R., Samuel, Varman T., Bhanot, Sanjay, Petersen, Kitt Falk, Jurczak, Michael J., Shulman, Gerald I.
Publicado no J Lipid Res (2015)

Anti-myostatin antibody increases muscle mass and strength and improves insulin sensitivity in old mice

Por Camporez, João-Paulo G., Petersen, Max C., Abudukadier, Abulizi, Moreira, Gabriela V., Jurczak, Michael J., Friedman, Glenn, Haqq, Christopher M., Petersen, Kitt Falk, Shulman, Gerald I.
Publicado no Proc Natl Acad Sci U S A (2016)

Cellular Mechanisms by Which FGF21 Improves Insulin Sensitivity in Male Mice

Por Camporez, João Paulo G., Jornayvaz, François R., Petersen, Max C., Pesta, Dominik, Guigni, Blas A., Serr, Julie, Zhang, Dongyan, Kahn, Mario, Samuel, Varman T., Jurczak, Michael J., Shulman, Gerald I.
Publicado em 2013

An Erk/Cdk5 axis controls the diabetogenic actions of PPARγ

Por Banks, Alexander S., McAllister, Fiona E., Camporez, João Paulo G., Zushin, Peter-James H., Jurczak, Michael J., Laznik-Bogoslavski, Dina, Shulman, Gerald I., Gygi, Steven P., Spiegelman, Bruce M.
Publicado no Nature (2014)

Saturated and unsaturated fat induce hepatic insulin resistance independently of TLR-4 signaling and ceramide synthesis in vivo

Por Galbo, Thomas, Perry, Rachel J., Jurczak, Michael J., Camporez‎, João-Paulo G., Alves, Tiago C., Kahn, Mario, Guigni, Blas A., Serr, Julie, Zhang, Dongyan, Bhanot, Sanjay, Samuel, Varman T., Shulman, Gerald I.
Publicado em 2013

Cellular Mechanism by Which Estradiol Protects Female Ovariectomized Mice From High-Fat Diet-Induced Hepatic and Muscle Insulin Resistance

Por Camporez, João Paulo G., Jornayvaz, François R., Lee, Hui-Young, Kanda, Shoichi, Guigni, Blas A., Kahn, Mario, Samuel, Varman T., Carvalho, Carla R.O., Petersen, Kitt Falk, Jurczak, Michael J., Shulman, Gerald I.
Publicado em 2013

Insulin-independent regulation of hepatic triglyceride synthesis by fatty acids

Por Vatner, Daniel F., Majumdar, Sachin K., Kumashiro, Naoki, Petersen, Max C., Rahimi, Yasmeen, Gattu, Arijeet K., Bears, Mitchell, Camporez, João-Paulo G., Cline, Gary W., Jurczak, Michael J., Samuel, Varman T., Shulman, Gerald I.
Publicado no Proc Natl Acad Sci U S A (2015)

Adipocyte JAK2 mediates growth hormone–induced hepatic insulin resistance

Por Corbit, Kevin C., Camporez, João Paulo G., Tran, Jennifer L., Wilson, Camella G., Lowe, Dylan A., Nordstrom, Sarah M., Ganeshan, Kirthana, Perry, Rachel J., Shulman, Gerald I., Jurczak, Michael J., Weiss, Ethan J.
Publicado no JCI Insight (2017)

Hepatic Mitogen-Activated Protein Kinase Phosphatase 1 Selectively Regulates Glucose Metabolism and Energy Homeostasis

Por Lawan, Ahmed, Zhang, Lei, Gatzke, Florian, Min, Kisuk, Jurczak, Michael J., Al-Mutairi, Mashael, Richter, Patric, Camporez, Joao Paulo G., Couvillon, Anthony, Pesta, Dominik, Roth Flach, Rachel J., Shulman, Gerald I., Bennett, Anton M.
Publicado no Mol Cell Biol (2014)

Fatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidism

Por Brown, Whitney H., Gillum, Matthew P., Lee, Hui-Young, Camporez, Joao Paulo G., Zhang, Xian-man, Jeong, Jin Kwon, Alves, Tiago C., Erion, Derek M., Guigni, Blas A., Kahn, Mario, Samuel, Varman T., Cravatt, Benjamin F., Diano, Sabrina, Shulman, Gerald I.
Publicado em 2012

Reduced intestinal lipid absorption and body weight-independent improvements in insulin sensitivity in high-fat diet-fed Park2 knockout mice

Por Costa, Diana K., Huckestein, Brydie R., Edmunds, Lia R., Petersen, Max C., Nasiri, Ali, Butrico, Gina M., Abulizi, Abudukadier, Harmon, Daniel B., Lu, Canying, Mantell, Benjamin S., Hartman, Douglas J., Camporez, João-Paulo G., O'Doherty, Robert M., Cline, Gary W., Shulman, Gerald I., Jurczak, Michael J.
Publicado no Am J Physiol Endocrinol Metab (2016)

CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER-preventing diacylglycerol-mediated hepatic insulin resistance

Por Cantley, Jennifer L., Yoshimura, Toru, Camporez, Joao Paulo G., Zhang, Dongyan, Jornayvaz, Francois R., Kumashiro, Naoki, Guebre-Egziabher, Fitsum, Jurczak, Michael J., Kahn, Mario, Guigni, Blas A., Serr, Julie, Hankin, Joseph, Murphy, Robert C., Cline, Gary W., Bhanot, Sanjay, Manchem, Vara Prasad, Brown, J. Mark, Samuel, Varman T., Shulman, Gerald I.
Publicado em 2013

Ablation of PRDM16 and Beige Adipose Causes Metabolic Dysfunction and a Subcutaneous to Visceral Fat Switch

Por Cohen, Paul, Levy, Julia D., Zhang, Yingying, Frontini, Andrea, Kolodin, Dmitriy P., Svensson, Katrin J., Lo, James C., Zeng, Xing, Ye, Li, Khandekar, Melin J., Wu, Jun, Gunawardana, Subhadra C., Banks, Alexander S., Camporez, João Paulo G., Jurczak, Michael J., Kajimura, Shingo, Piston, David W., Mathis, Diane, Cinti, Saverio, Shulman, Gerald I., Seale, Patrick, Spiegelman, Bruce M.
Publicado em 2014

Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes

Por Perry, Rachel J., Camporez, João-Paulo G., Kursawe, Romy, Titchenell, Paul M., Zhang, Dongyan, Perry, Curtis J., Jurczak, Michael J., Abudukadier, Abulizi, Han, Myoung Sook, Zhang, Xian-Man, Ruan, Hai-Bin, Yang, Xiaoyong, Caprio, Sonia, Kaech, Susan M., Sul, Hei Sook, Birnbaum, Morris J., Davis, Roger J., Cline, Gary W., Petersen, Kitt Falk, Shulman, Gerald I.
Publicado no Cell (2015)

17α-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization

Por Stout, Michael B., Steyn, Frederik J., Jurczak, Michael J., Camporez, Joao-Paulo G., Zhu, Yi, Hawse, John R., Jurk, Diana, Palmer, Allyson K., Xu, Ming, Pirtskhalava, Tamar, Evans, Glenda L., de Souza Santos, Roberta, Frank, Aaron P., White, Thomas A., Monroe, David G., Singh, Ravinder J., Casaclang-Verzosa, Grace, Miller, Jordan D., Clegg, Deborah J., LeBrasseur, Nathan K., von Zglinicki, Thomas, Shulman, Gerald I., Tchkonia, Tamara, Kirkland, James L.
Publicado no J Gerontol A Biol Sci Med Sci (2017)