Cellular Mechanisms by Which FGF21 Improves Insulin Sensitivity in Male Mice

Fibroblast growth factor 21 (FGF21) is a potent regulator of glucose and lipid metabolism and is currently being pursued as a therapeutic agent for insulin resistance and type 2 diabetes. However, the cellular mechanisms by which FGF21 modifies insulin action in vivo are unclear. To address this que...

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Detalhes bibliográficos
Main Authors: Camporez, João Paulo G., Jornayvaz, François R., Petersen, Max C., Pesta, Dominik, Guigni, Blas A., Serr, Julie, Zhang, Dongyan, Kahn, Mario, Samuel, Varman T., Jurczak, Michael J., Shulman, Gerald I.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
Assuntos:
Diabetes-Insulin-Glucagon-Gastrointestinal
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749479/
https://ncbi.nlm.nih.gov/pubmed/23766126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-1191
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