Thyroid Hormone Receptor-α Gene Knockout Mice Are Protected from Diet-Induced Hepatic Insulin Resistance

Nonalcoholic fatty liver disease (NAFLD) is the most frequent chronic liver disease in the United States and is strongly associated with hepatic insulin resistance. We examined whether the thyroid hormone receptor-α (Thra) would be a potential therapeutic target to prevent diet-induced NAFLD and ins...

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Hlavní autoři: Jornayvaz, François R., Lee, Hui-Young, Jurczak, Michael J., Alves, Tiago C., Guebre-Egziabher, Fitsum, Guigni, Blas A., Zhang, Dongyan, Samuel, Varman T., Silva, J. Enrique, Shulman, Gerald I.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2012
Témata:
Diabetes-Insulin-Glucagon-Gastrointestinal
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384074/
https://ncbi.nlm.nih.gov/pubmed/22147010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1793
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