Thyroid Hormone Receptor-α Gene Knockout Mice Are Protected from Diet-Induced Hepatic Insulin Resistance

Nonalcoholic fatty liver disease (NAFLD) is the most frequent chronic liver disease in the United States and is strongly associated with hepatic insulin resistance. We examined whether the thyroid hormone receptor-α (Thra) would be a potential therapeutic target to prevent diet-induced NAFLD and ins...

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Detalhes bibliográficos
Main Authors: Jornayvaz, François R., Lee, Hui-Young, Jurczak, Michael J., Alves, Tiago C., Guebre-Egziabher, Fitsum, Guigni, Blas A., Zhang, Dongyan, Samuel, Varman T., Silva, J. Enrique, Shulman, Gerald I.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
Diabetes-Insulin-Glucagon-Gastrointestinal
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384074/
https://ncbi.nlm.nih.gov/pubmed/22147010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1793
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