Thyroid Hormone Receptor-α Gene Knockout Mice Are Protected from Diet-Induced Hepatic Insulin Resistance

Nonalcoholic fatty liver disease (NAFLD) is the most frequent chronic liver disease in the United States and is strongly associated with hepatic insulin resistance. We examined whether the thyroid hormone receptor-α (Thra) would be a potential therapeutic target to prevent diet-induced NAFLD and ins...

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Bibliographic Details
Main Authors: Jornayvaz, François R., Lee, Hui-Young, Jurczak, Michael J., Alves, Tiago C., Guebre-Egziabher, Fitsum, Guigni, Blas A., Zhang, Dongyan, Samuel, Varman T., Silva, J. Enrique, Shulman, Gerald I.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2012
Subjects:
Diabetes-Insulin-Glucagon-Gastrointestinal
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384074/
https://ncbi.nlm.nih.gov/pubmed/22147010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1793
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