Hepatic insulin resistance in mice with hepatic overexpression of diacylglycerol acyltransferase 2

Mice overexpressing acylCoA:diacylglycerol (DAG) acyltransferase 2 in the liver (Liv-DGAT2) have been shown to have normal hepatic insulin responsiveness despite severe hepatic steatosis and increased hepatic triglyceride, diacylglycerol, and ceramide content, demonstrating a dissociation between he...

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Detalhes bibliográficos
Main Authors: Jornayvaz, François R., Birkenfeld, Andreas L., Jurczak, Michael J., Kanda, Shoichi, Guigni, Blas A., Jiang, Debbie C., Zhang, Dongyan, Lee, Hui-Young, Samuel, Varman T., Shulman, Gerald I.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078388/
https://ncbi.nlm.nih.gov/pubmed/21436037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103451108
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