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Insulin-independent regulation of hepatic triglyceride synthesis by fatty acids

A central paradox in type 2 diabetes is the apparent selective nature of hepatic insulin resistance—wherein insulin fails to suppress hepatic glucose production yet continues to stimulate lipogenesis, resulting in hyperglycemia, hyperlipidemia, and hepatic steatosis. Although efforts to explain this...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Vatner, Daniel F., Majumdar, Sachin K., Kumashiro, Naoki, Petersen, Max C., Rahimi, Yasmeen, Gattu, Arijeet K., Bears, Mitchell, Camporez, João-Paulo G., Cline, Gary W., Jurczak, Michael J., Samuel, Varman T., Shulman, Gerald I.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313795/
https://ncbi.nlm.nih.gov/pubmed/25564660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423952112
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