Pol κ in replication checkpoint

Por Maiorano, Domenico, Hoffmann, Jean-Sébastien
Publicado em 2013

Proper sister chromatid disjunction requires CDA and PARP-1

Por Hoffmann, Jean-Sébastien, Cordelier, Pierre
Publicado no Cell Cycle (2017)

The Protective Role of Dormant Origins in Response to Replicative Stress

Por Courtot, Lilas, Hoffmann, Jean-Sébastien, Bergoglio, Valérie
Publicado no Int J Mol Sci (2018)

Impact of the DNA polymerase Theta on the DNA replication program

Por Baldacci, Giuseppe, Hoffmann, Jean-Sebastien, Cadoret, Jean-Charles
Publicado no Genom Data (2014)

Role of DNA polymerase κ in the maintenance of genomic stability

Por Pillaire, Marie-Jeanne, Bétous, Rémy, Hoffmann, Jean-Sébastien
Publicado no Mol Cell Oncol (2014)

Targeting ATR/CHK1 pathway in acute myeloid leukemia to overcome chemoresistance

Por David, Laure, Manenti, Stéphane, Récher, Christian, Hoffmann, Jean-Sébastien, Didier, Christine
Publicado no Mol Cell Oncol (2017)

Overexpression of DNA polymerase β in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs

Por Canitrot, Yvan, Cazaux, Christophe, Fréchet, Mathilde, Bouayadi, Khalil, Lesca, Claire, Salles, Bernard, Hoffmann, Jean-Sébastien
Publicado em 1998

DNA polymerase β overexpression stimulates the Rad51-dependent homologous recombination in mammalian cells

Por Canitrot, Yvan, Capp, Jean-Pascal, Puget, Nadine, Bieth, Anne, Lopez, Bernard, Hoffmann, Jean-Sébastien, Cazaux, Christophe
Publicado em 2004

Involvement of DNA polymerase μ in the repair of a specific subset of DNA double-strand breaks in mammalian cells

Por Capp, Jean-Pascal, Boudsocq, François, Besnard, Anne-Gaelle, Lopez, Bernard S., Cazaux, Christophe, Hoffmann, Jean-Sébastien, Canitrot, Yvan
Publicado em 2007

A DNA repair variant in POLQ (c.-1060A > G) is associated to hereditary breast cancer patients: a case–control study

Por Brandalize, Ana Paula Carneiro, Schüler-Faccini, Lavínia, Hoffmann, Jean-Sébastien, Caleffi, Maira, Cazaux, Christophe, Ashton-Prolla, Patricia
Publicado no BMC Cancer (2014)

MUS81 nuclease activity is essential for replication stress tolerance and chromosome segregation in BRCA2-deficient cells

Por Lai, Xianning, Broderick, Ronan, Bergoglio, Valérie, Zimmer, Jutta, Badie, Sophie, Niedzwiedz, Wojciech, Hoffmann, Jean-Sébastien, Tarsounas, Madalena
Publicado no Nat Commun (2017)

Corrigendum: MUS81 nuclease activity is essential for replication stress tolerance and chromosome segregation in BRCA2-deficient cells

Por Lai, Xianning, Broderick, Ronan, Bergoglio, Valérie, Zimmer, Jutta, Badie, Sophie, Niedzwiedz, Wojciech, Hoffmann, Jean-Sébastien, Tarsounas, Madalena
Publicado no Nat Commun (2017)

Fork-like DNA templates support bypass replication of lesions that block DNA synthesis on single-stranded templates

Por Hoffmann, Jean-Sébastien, Pillaire, Marie-Jeanne, Lesca, Claire, Burnouf, Dominique, Fuchs, Robert P. P., Defais, Martine, Villani, Giuseppe
Publicado em 1996

Active Site Mutations in Mammalian DNA Polymerase δ Alter Accuracy and Replication Fork Progression

Por Schmitt, Michael W., Venkatesan, Ranga N., Pillaire, Marie-Jeanne, Hoffmann, Jean-Sébastien, Sidorova, Julia M., Loeb, Lawrence A.
Publicado em 2010

DNA replication stress triggers rapid DNA replication fork breakage by Artemis and XPF

Por Bétous, Rémy, Goullet de Rugy, Théo, Pelegrini, Alessandra Luiza, Queille, Sophie, de Villartay, Jean-Pierre, Hoffmann, Jean-Sébastien
Publicado no PLoS Genet (2018)

Human DNA Polymerase η Is Required for Common Fragile Site Stability during Unperturbed DNA Replication

Por Rey, Laurie, Sidorova, Julia M., Puget, Nadine, Boudsocq, François, Biard, Denis S. F., Monnat, Raymond J., Cazaux, Christophe, Hoffmann, Jean-Sébastien
Publicado em 2009

Human Adipose‐Derived Stem Cells Expanded Under Ambient Oxygen Concentration Accumulate Oxidative DNA Lesions and Experience Procarcinogenic DNA Replication Stress

Por Bétous, Rémy, Renoud, Marie‐Laure, Hoede, Claire, Gonzalez, Ignacio, Jones, Natalie, Longy, Michel, Sensebé, Luc, Cazaux, Christophe, Hoffmann, Jean‐Sébastien
Publicado no Stem Cells Transl Med (2016)

The DNA polymerase λ is required for the repair of non-compatible DNA double strand breaks by NHEJ in mammalian cells

Por Capp, Jean-Pascal, Boudsocq, François, Bertrand, Pascale, Laroche-Clary, Audrey, Pourquier, Philippe, Lopez, Bernard S., Cazaux, Christophe, Hoffmann, Jean-Sébastien, Canitrot, Yvan
Publicado em 2006

DNA synthesis by Pol η promotes fragile site stability by preventing under-replicated DNA in mitosis

Por Bergoglio, Valérie, Boyer, Anne-Sophie, Walsh, Erin, Naim, Valeria, Legube, Gaëlle, Lee, Marietta Y.W.T., Rey, Laurie, Rosselli, Filippo, Cazaux, Christophe, Eckert, Kristin A., Hoffmann, Jean-Sébastien
Publicado em 2013

Cyclin Kinase-independent role of p21(CDKN1A) in the promotion of nascent DNA elongation in unstressed cells

Por Mansilla, Sabrina F, Bertolin, Agustina P, Bergoglio, Valérie, Pillaire, Marie-Jeanne, González Besteiro, Marina A, Luzzani, Carlos, Miriuka, Santiago G, Cazaux, Christophe, Hoffmann, Jean-Sébastien, Gottifredi, Vanesa
Publicado no eLife (2016)