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DNA polymerase β overexpression stimulates the Rad51-dependent homologous recombination in mammalian cells

Overexpression of DNA polymerase β (polβ), an error-prone DNA repair enzyme, has been shown to result in mutagenesis, aneuploidy and tumorigenesis. To further investigate the molecular basis leading to cancer-associated genetic changes, we examined whether the DNA polβ could affect homologous recomb...

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Detalhes bibliográficos
Main Authors: Canitrot, Yvan, Capp, Jean-Pascal, Puget, Nadine, Bieth, Anne, Lopez, Bernard, Hoffmann, Jean-Sébastien, Cazaux, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC521661/
https://ncbi.nlm.nih.gov/pubmed/15452277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh848
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