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Involvement of DNA polymerase μ in the repair of a specific subset of DNA double-strand breaks in mammalian cells

The repair of DNA double-strand breaks (DSB) requires processing of the broken ends to complete the ligation process. Recently, it has been shown that DNA polymerase μ (polμ) and DNA polymerase λ (polλ) are both involved in such processing during non-homologous end joining in vitro. However, no phen...

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Hlavní autoři: Capp, Jean-Pascal, Boudsocq, François, Besnard, Anne-Gaelle, Lopez, Bernard S., Cazaux, Christophe, Hoffmann, Jean-Sébastien, Canitrot, Yvan
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1920243/
https://ncbi.nlm.nih.gov/pubmed/17483519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm243
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