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RAD51 supports spontaneous non-homologous recombination in mammalian cells, but not the corresponding process induced by topoisomerase inhibitors

The RAD51 protein has been shown to participate in homologous recombination by promoting ATP-dependent homologous pairing and strand transfer reactions. In the present study, we have investigated the possible involvement of RAD51 in non-homologous recombination. We demonstrate that overexpression of...

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Bibliographische Detailangaben
Hauptverfasser: Arnaudeau, Catherine, Rozier, Lorène, Cazaux, Christophe, Defais, Martine, Jenssen, Dag, Helleday, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2001
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC30407/
https://ncbi.nlm.nih.gov/pubmed/11160887
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